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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
10.5 DPC

21 matching records from 21 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tbx2  T-box 2  
Results  Reference
1*J:177580 Begum S, Papaioannou VE, Dynamic expression of Tbx2 and Tbx3 in developing mouse pancreas. Gene Expr Patterns. 2011 Dec;11(8):476-83
1J:120113 Behesti H, Holt JK, Sowden JC, The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup. BMC Dev Biol. 2006;6:62
1*J:152494 Behesti H, Papaioannou VE, Sowden JC, Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Dev Biol. 2009 Sep 15;333(2):360-72
1*J:89198 Christoffels VM, Hoogaars WM, Tessari A, Clout DE, Moorman AF, Campione M, T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers. Dev Dyn. 2004 Apr;229(4):763-70
1J:113522 Deng J, Dekruyff RH, Freeman GJ, Umetsu DT, Levy S, Critical role of CD81 in cognate T-B cell interactions leading to Th2 responses. Int Immunol. 2002 May;14(5):513-23
1J:200023 Farin HF, Ludtke TH, Schmidt MK, Placzko S, Schuster-Gossler K, Petry M, Christoffels VM, Kispert A, Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1. PLoS Genet. 2013;9(4):e1003467
1J:159210 Galli A, Robay D, Osterwalder M, Bao X, Benazet JD, Tariq M, Paro R, Mackem S, Zeller R, Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet. 2010;6(4):e1000901
1*J:316178 Gamart J, Barozzi I, Laurent F, Reinhardt R, Martins LR, Oberholzer T, Visel A, Zeller R, Zuniga A, SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Development. 2021 Dec 1;148(23):dev200182
1*J:33697 Gibson-Brown JJ, Agulnik SI, Chapman DL, Alexiou M, Garvey N, Silver LM, Papaioannou VE, Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity. Mech Dev. 1996 May;56(1-2):93-101
1J:113422 Harrelson Z, Papaioannou VE, Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis. Dev Dyn. 2006 Nov;235(11):3080-4
1J:102855 Jerome-Majewska LA, Jenkins GP, Ernstoff E, Zindy F, Sherr CJ, Papaioannou VE, Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway. Dev Dyn. 2005 Dec;234(4):922-33
1J:312493 Jhanwar S, Malkmus J, Stolte J, Romashkina O, Zuniga A, Zeller R, Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development. Nat Commun. 2021 Sep 28;12(1):5685
1*J:226028 Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA, Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
1*J:83256 Naiche LA, Papaioannou VE, Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois. Development. 2003 Jun;130(12):2681-93
1*J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1J:154674 Shirai M, Imanaka-Yoshida K, Schneider MD, Schwartz RJ, Morisaki T, T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18604-9
1J:332291 Song H, Morrow BE, Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle for inner ear development. Dev Biol. 2022 Dec 12;494:71-84
1J:73310 Sowden JC, Holt JK, Meins M, Smith HK, Bhattacharya SS, Expression of Drosophila omb-Related T-Box Genes in the Developing Human and Mouse Neural Retina. Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3095-102
1J:188772 Voss AK, Vanyai HK, Collin C, Dixon MP, McLennan TJ, Sheikh BN, Scambler P, Thomas T, MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome. Dev Cell. 2012 Sep 11;23(3):652-63
1*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1J:154920 Zirzow S, Ludtke TH, Brons JF, Petry M, Christoffels VM, Kispert A, Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Dev Biol. 2009 Dec 15;336(2):145-55

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory